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pentobarbital will lessen the level or result of parecoxib by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Keep track of.pentobarbital decreases levels of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Robust CYP3A4 inducers can lessen panobinostat amounts by ~70% and lead to procedure failur